Curriculum & Course Descriptions

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BS7005 Practical Course in Multidimensional NMR spectroscopy

Course Coordinator: Associate Professor Konstantin PERVUSHIN (email: Kpervushin@ntu.edu.sg)

Availability: Semester 2

This course is designed particularly for Graduate students, who already have a basic knowledge in structural biology. The course will contain the foundational basis of NMR theory, but will be primarily focused on the development and enhancing of practical skills in the use of the advanced NMR techniques in applications to such research areas as protein structure and dynamics determination, high through put ligand screening as well as rapid analysis of protein states.

Topics:

  • NMR spectroscopy: An Introduction
  • Energy levels and NMR spectra
  • The vector model
  • Fourier transformation
  • Product operators
  • Two dimensional NMR
  • Introduction to 3D NMR
  • Structure validation