Bozdech, Zbynek


Selected Publications

  1. Foth, B. J. et al. Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics 10, M110 006411, doi:10.1074/mcp.M110.006411 (2011).
  2. Foth, B. J., Zhang, N., Mok, S., Preiser, P. R. & Bozdech, Z. Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites. Genome Biol 9, R177, doi:10.1186/gb-2008-9-12-r177 (2008).
  3. Bozdech, Z. et al. The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites. Proc Natl Acad Sci U S A 105, 16290-16295, doi:10.1073/pnas.0807404105 (2008).
  4. Bozdech, Z. et al. The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol 1, E5, doi:10.1371/journal.pbio.0000005 (2003).
  5. Andrews, K. T. et al. Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors. PLoS One 7, e31847, doi:10.1371/journal.pone.0031847 (2012).
  6. Luah, Y. H., Chaal, B. K., Ong, E. Z. & Bozdech, Z. A moonlighting function of Plasmodium falciparum histone 3, mono-methylated at lysine 9? PLoS One 5, e10252, doi:10.1371/journal.pone.0010252 (2010).
  7. Chaal, B. K., Gupta, A. P., Wastuwidyaningtyas, B. D., Luah, Y. H. & Bozdech, Z. Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle. PLoS Pathog 6, e1000737, doi:10.1371/journal.ppat.1000737 (2010).
  8. Witmer, K. et al. Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling. Mol Microbiol 84, 243-259, doi:10.1111/j.1365-2958.2012.08019.x (2012).
  9. Kuss, C. et al. Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum. Mol Cell Proteomics 11, M111 010645, doi:10.1074/mcp.M111.010645 (2012).
  10. Claessens, A. et al. A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc Natl Acad Sci U S A 109, E1772-1781, doi:10.1073/pnas.1120461109 (2012).
  11. Claessens, A. et al. Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes. Malar J 10, 180, doi:10.1186/1475-2875-10-180 (2011).
  12. Flueck, C. et al. A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology. PLoS Pathog 6, e1000784, doi:10.1371/journal.ppat.1000784 (2010).
  13. Flueck, C. et al. Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors. PLoS Pathog 5, e1000569, doi:10.1371/journal.ppat.1000569 (2009).
  14. Rovira-Graells, N. et al. Transcriptional variation in the malaria parasite Plasmodium falciparum. Genome Res 22, 925-938, doi:10.1101/gr.129692.111 (2012).
  15. Mok, S. et al. Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription. BMC Genomics 12, 391, doi:10.1186/1471-2164-12-391 (2011).
  16. Mackinnon, M. J. et al. Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates. PLoS Pathog 5, e1000644, doi:10.1371/journal.ppat.1000644 (2009).
  17. Hu, G. et al. Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum. Nat Biotechnol 28, 91-98, doi:10.1038/nbt.1597 (2010).