Thibault, Guillaume


Selected Publications

  1. H. Wu, B.S.H Ng, G. Thibault (2014). Endoplasmic Reticulum Stress Response in Yeast and Humans. Biosci Rep.34(4):art:e00118.doi:10.1042/BSR20140058
  2. C. Xu, S. Wang, G. Thibault, D.T. W. Ng (2013). Futile Protein Folding Cycles in the ER are Terminated by the Unfolded O-mannosylation Pathway. Science 340, 978-981. Perspective in Science.
  3. G. Thibault, D.T.W. Ng (2013). Heat/Stress Responses. Encyclopedia of Biological Chemistry, Academic Press, Waltham, 2013, 522-525.
  4. G. Thibault, D.T.W. Ng (2012). The Endoplasmic Reticulum-Associated Degradation Pathways of Budding Yeast. Cold Spring Harb Perspect Biol 2012 Dec 3;4(12):a013193.
  5. G. Thibault, G. Shui, W. Kim, G.C. McAlister, N. Ismail, S.P. Gygi, M.R (2012). Wenk, D.T.W. Ng. The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network. Mol Cell 48, 16-27. Featured on the cover and Faculty of 1000 evaluation.
  6. G. Thibault, W.A. Houry (2012). The role of the N-terminal domain of the chaperone ClpX in recognition and degradation of lambda phage protein O. J Phys Chem B 116, 6717-6724.
  7. G. Thibault*, N. Ismail*, D.T.W. Ng (2011). The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway. Proc Natl Acad Sci U S A108, 20597-20602. *co-first authors.
  8. S. Wang, G. Thibault, D.T.W. Ng (201!). Routing misfolded proteins through the multivesicular body (MVB) pathway protects against proteotoxicity. J Biol Chem 286, 29376-23987.
  9. G. Thibault, D.T.W Ng (2011). A screen for mutants requiring activation of the unfolded protein response for viability. Methods Enzymol 491, 199-216.
  10. U. Kanjee, I. Gutsche, E. Alexopoulos, B. Zhao, G. Thibault, K. Liu, S. Ramachandran, J. Snider, E.F. Pai. W.A. Houry (2011). Linkage between the bacterial acid stress and stringent responses: The structure of the inducible lysine decarboxylase. EMBO J 30, 931-944. Faculty of 1000 evaluation.
  11. J. Snider*, G. Thibault*, W.A. Houry (2008). The AAA+ superfamily of functionally diverse proteins. Genome Biol9, 216. *co-first authors.
  12. G. Thibault, J. Yudin, P. Wong, V. Tsitrin, R. Sprangers, R. Zhao, W. A Houry (2006). Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX. Proc Natl Acad Sci U S A 103, 17724-17729.
  13. G. Thibault*, Y. Tsitrin*, T. Davidson, A. Gribun, W.A. Houry (2006). Large-scale nucleotide-dependent movement of the N-terminal zinc binding domain of ClpX: implications for chaperone function and regulation. EMBO J 25, 3367-3376. *co-first authors.
  14. U. A. Wojtyra*, G. Thibault*, A. Tuite, W. A. Houry (2003). The N-terminal zinc binding domain of ClpX is a substrate sensing and dimerization domain that modulates the chaperone function. J Biol Chem 278, 48981-48990. *co-first authors.