Sugrue, Richard


Selected Publications

  1. Anuradha Radhakrishnan, Dawn Yeo, Gaie Brown, Myint Zu Myaing, Laxmi Ravi Iyer, Roland Fleck, Boon-Huan Tan, Jim Aitken, Duangmanee Sanmun, Kai Tang, Andy Yarwood, Jacob Brink and Richard J Sugrue. (2010) . Protein analysis of purified respiratory syncytial virus particles reveals an important role for heat shock protein 90 in virus particle assembly. Molecular and Cellular Proteomics (in press)
  2. Tan BH, Loo LH, Lim EA, Kheng Seah SL, Lin RT, Tee NW, Sugrue RJ. Human rhinovirus group C in hospitalized children, Singapore. Emerg Infect Dis. 2009 15(8):1318-20.
  3. Richard J Sugrue, Boon Huan Tan, and Liat Hui Loo. (2008). The emergence of human metapneumovirus. (review) Future Virology. 3, 363-371.
  4. Tan BH, Lim EA, Seah SG, Loo LH, Tee NW, Lin RT, Sugrue RJ. The incidence of human bocavirus infection among children admitted to hospital in Singapore.(2009) J Med Virol. 81, 82-9.
  5. Yeo DS, Chan R, Brown G, Ying L, Sutejo R, Aitken J, Tan BH, Wenk MR, Sugrue RJ. Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection.(2009) Virology. In press
  6. Kit Wei Low, Timothy Tan, Ken Ng, Boon-Huan Tan and Richard J Sugrue (2007). The RSV F and G glycoproteins interact to form a complex on the surface of infected cells. BBRC. in press.
  7. Liat Hui Loo, Boon Huan Tan, Ley Moy Ng, Nancy WS Tee, Raymond TP Lin and Richard J Sugrue. (2007). Human metapneumovirus in children, Singapore. Emerging Infectious Diseases, CDC. 13, 1396-1398.
  8. Chris E. Jeffree, Gaie Brown, Jim Aitken, Dawn Yeo Su-Yin, Boon-Huan Tan and Richard J. Sugrue (2007). Ultrastructural analysis of the interaction between F-actin and respiratory syncytial virus during virus assembly. Virology. In press
  9. Glycovirology protocols (2007). Methods in Molecular Biology. (Ed by RJ Sugrue). Humana Press, NJ, USA. in press
  10. Sugrue RJ. (2006). Interactions between respiratory syncytial virus and the host cell: opportunities for new antivirus strategies? Expert Reviews in Molecular Medicine, Cambridge University Press. UK in press
  11. McDonald, T.P., Jeffree, C.E., Li, P., Rixon, H.W., Brown, G., Aitken, J.D., Maclellan, K. and Sugrue, R.J. (2006). Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of alpha-mannosidase inhibitors on RSV infectivity. Virology. 350, 289-301
  12. Brown G, Rixon HW, Steel J, McDonald TP, Pitt AR, Graham S, Sugrue RJ. (2005). Evidence for an association between heat shock protein 70 and the respiratory syncytial virus polymerase complex within lipid-raft membranes during virus infection. Virology. 338, 69-80.
  13. Rixon HW, Brown G, Murray JT, Sugrue RJ. (2005). The respiratory syncytial virus small hydrophobic protein is phosphorylated via a mitogen-activated protein kinase p38-dependent tyrosine kinase activity during virus infection. Journal of General Virology 86, 375-84.
  14. McDonald TP, Pitt AR, Brown G, Rixon H. W. McL, Sugrue RJ. (2004). Evidence that the respiratory syncytial virus polymerase complex associates with lipid rafts in virus-infected cells: a proteomic analysis. Virology. 330, 147-57.
  15. Brown G, Jeffree C.E, McDonald T, Rixon H. W. McL , Aitken JD, Sugrue RJ. (2004). Analysis of the interaction between respiratory syncytial virus and lipid-rafts in Hep2 cells during infection. Virology. 327, 175-85.
  16. Rixon, H. W. McL., Brown, G., Aitken, J., McDonald, T.,Graham, S. and Sugrue, R.J. (2004). The small hydrophobic (SH) protein accumulates within lipid-raft structures of the Golgi complex during respiratory syncytial virus (RSV) infection. (2004). Journal of General Virology 85, 1153-65.
  17. Boon-Huan Tan, Eu-Hian Yap and Richard J. Sugrue. (2004) Prospects for antiviral strategies in the treatment and prevention of Dengue virus infections (review). Current Virology, Research trends 4, 21-37.
  18. Jeffree, C.E. Rixon, H. W. McL., Brown, G., Aitken, J., and. Sugrue, R. J. (2003) Distribution of the Attachment (G) Glycoprotein and GM1 Within the Envelope of Mature Respiratory Syncytial Virus Filaments Revealed Using Field Emission Scanning Electron Microscopy. Virology 306, 254-267.
  19. Brown, G., Rixon, H. W. McL. and Sugrue., R.J. (2002) Respiratory syncytial virus assembly occurs in GM1-rich regions of the host cell membrane and alters the cellular distribution of tyrosine phosphorylated caveolin-1. Journal of General Virology 83, 1841-50.
  20. Brown, G., Aitken, J., Rixon, H. W. McL and Sugrue, R.J. (2002) Caveolin-1 is incorporated into mature RSV particles during virus assembly on the surface of virus-infected cells. Journal of General Virology 83, 611-621