Ohlson, Sten


Selected Publications

  1. Larsson, PO, Ohlson, S, and Mosbach, K; New approach to steroid conversion using immobilised microorganisms. Nature 263:796-7907 (1976).
  2. Zopf, D. and Ohlson, S.: Weak-affinity chromatography. Nature 346:87-88. (1990).
  3. Ohlson, S, Jungar, C, Strandh, M, and Mandenius, C-F: Continuous weak-affinity immunosensing. Trends in Biotechnology 18:49-52. (2000).
  4. Ohlson, S, Strandh, M, and Nilshans, H: Detection and characterization of weak affinity anti-body-antigen recognition with biomolecular interaction analysis. Journal of Molecular Recognition 10:135-138. (1997).
  5. Ohlson, S, Hansson, L, Glad, M, Mosbach, K, and Larsson, PO: High Performance Liquid Affinity Chromatography: A new tool in biotechnology. Trends in Biotechnology 7:179-186. (1989).
  6. Aldén, A, Gonzalez, L, Persson, A, Christenson, K, Holmqvist, O, and Ohlson, S: Porcine platelet lysate as a supplement for animal cell culture. Cytotechnology 55(1): 3-8. (2007).
  7. Ramos-Soriano, J, Niss, U, Angulo, J, Angulo, M, Moreno-Vargas, AJ, Carmona, AT, Ohlson, S and Robina, I: Synthesis, biological evaluation, WAC and NMR studies of S-galactosides and non-carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties. Chemistry: European Journal, doi: 10.1002/chem.201302786 (2013).
  8. Landström J, Bergström M, Hamark C, Ohlson S, Widmalm G: Combining weak affinity chromatography, NMR spectroscopy and molecular simulations in carbohydrate-lysozyme interaction studies. Organic & Biomolecular Chemistry 10(15):3019-3032. (2012).
  9. Bergström M, Åström E, Påhlsson P, Ohlson S: Elucidating the selectivity of recombinant forms of aleuria aurantia lectin using weak affinity chromatography. Journal of Chromatography B 885-886:66-72 (2012).
  10. Duong-Thi MD, Meiby E, Bergstrom M, Fex T, Isaksson R, Ohlson S: Weak affinity chromatography as a new approach for fragment screening in drug discovery. Analytical Biochemistry 414(1):138-146 (2011).
  11. Meiby E, Simmonite H, Davis B, le Strat L, Matassova J, Mrosek M, Murray J, Hubbard R, Ohlson S: Fragment screening by weak affinity chromatography (wac): Comparison with established techniques for screening against hsp90. Analytical Chemistry 85, 6756-6766 (2013).
  12. Duong-Thi MD, Bergström M, Fex T, Isakson R, Ohlson S: High-throughput fragment screening by affinity lc-ms. Journal of Biomolecular Screening 18(2):160-171 (2013).
  13. Meiby E, Knapp S, Elkins J, Ohlson S: Fragment screening of cyclin g-associated kinase by weak affinity chromatography. Analytical and Bioanalytical Chemistry 404(8):2417-2425 (2012).
  14. Meiby E, Zetterberg MM, Ohlson S, Hernández VA, Edwards K: Immobilized lipodisks as model membranes in high throughput hplc-ms analysis. Analytical and Bioanalytical Chemistry 405(14):4859-4869 (2013).
  15. Duong-Thi MD, Bergström M, Fex T, Svensson S, Ohlson S, Isaksson R: Weak affinity chromatography for evaluation of stereoisomers in early drug discovery. Journal of Biomolecular Screening 18, 6:748-755 (2013).
  16. Ohlson S: Designing transient binding drugs: A new concept for drug discovery. Drug Discovery Today 13(9-10):433a-439 (2008).
  17. Torres AR, Ohlson S: Weak Affinity Chromatography. US provisional patent application No.: 61873709 (2013).
  18. Ohlson S: New molecularly imprinted polymer and method for its production. PCT Patent Application WO 2010/085207 A1 (2010).

Research Grants
National Medical Research Council (NMRC) (2013- )
Start-up grant (SUG) (2013- )
Numerous grants from Swedish research foundation including the Swedish Research Council and also major support from the life-science industry.