Tan Nguan Soon, Andrew

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Selected Publications

2018

  1. Sng, M.K., Chan, J.S.K., Teo, Z.Q., Phua, T., Tan, E.H.P., Wee, J.W.W., Koh, N.J.N., Tan, C.K., Chen, J., Pal, M., Tong, B.M.K., Tnay, Y.L., Ng, X.R., Zhu, P.C., Chiba, S., Wang, X., Wahli, W. and Tan, N.S. (2018) Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. Cell Discov. (in press)
  2. Tan, E.H.P., Sng, M.K., How, I.S.B., Chan, J.S.K., Chen, J., Tan, C.K., Wahli, W. and Tan, N.S. (2018) ROS release by PPARb/δ-null fibroblasts reduces tumor load through epithelial antioxidant response. Oncogene doi:10.1038/s41388-017-0109-8
  3. Liao, Z., Tan, Z.W., Zhu, P.C., and Tan, N.S. (2018) Cancer-associated fibroblasts in tumor microenvironment–accomplices in tumor malignancy. Cell Immunol. pii: S0008-8749(17)30222-8. doi 10.1016/j.cellimm.2017.12.003 (review)
  4. Chan, J.S.K., Sng, M.K., Teo, Z.Q., Chong, H.C., Twang, J.S. and Tan, N.S. (2018) Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors. Oncogene; 37(2):160-173. doi: 10.1038/onc.2017.319

2017

  1. Guneta. V., Zhou, Z., Tan, N.S., Sugii, S., Wong, M.T.C. and Choong, C. (2017) Recellularization of decellularized adipose tissue-derived stem cells: role of the cell-secreted extracellular matrix in cellular differentiation. Biomater Sci. Nov 23. doi: 10.1039/c7bm00695k.
  2. Hou, Z., Shankar, Y.V., Liu, Y., Ding, F., Subramanion, J.L., Ravikumar, V., Zamudio-Vázquez, R., Keogh, D., Lim, H., Tay, M.Y.F., Bhattacharjya, S., Rice, S.A., Shi, J., Duan, H., Liu, X.W., Mu, Y., Tan, N.S., Tam, K.M.C., Pethe, K. and Chan-Park, M.B. (2017) Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multi-Drug Resistant Bacteria. ACS Appl Mater Interfaces. Oct 13. 9(44):38288-38303. doi: 10.1021/acsami.7b12120.
  3. Wang, J.K., Yeo, K.P., Chun, Y.Y., Tan, T., Tan, N.S., Angeli, V. and Choong, C. (2017) Fish scale-derived collagen patch promotes growth of blood and lymphatic vessels in vivo. Acta Biomater.Sep 6. pii: S1742-7061(17)30564-0.
    Baek, J-S., Choo, C.C., Tan, N.S. and Loo, S.C.J. (2017) Sustained-releasing Hollow Microparticles with Dual-anticancer Drugs Elicit Greater Shrinkage of Tumor Spheroids. Oncotarget 8:80841-80852.
  4. Ku, C.W., Tan, Z.W., Lim, M.K., Tam, Z.Y., Lin, C-H., Ng, S.P., Allen, J.C., Lek, S.M., Tan, T.C. and Tan, N.S. (2017) Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile. BBA Clin. 8:48-55. doi: 10.1016/j.bbacli.2017.07.003.
  5. Kalailingam, P., Tan, H.B., Jain, N., Sng, M.K., Chan, J.S.K., Tan, N.S. and Thanabalu, T. (2017) Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation. Sci Rep. 7: 7311. doi:10.1038/s41598-017-07125-8.
  6. Teo, Z.Q., Sng, M.K., Chan, J.S.K., Lim, M.M.K., Li, Y.L., Phua, T., Lee, J.Y.H., Tan, Z.W., Zhu, P.C. and Tan, N.S. (2017) Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial-mesenchymal transition by inducing 14-3-3γ expression. Oncogene Jul 24. doi: 10.1038/onc.2017.244.
  7. Teo, Z.Q., Chan, J.S.K., Chong, H.C., Sng, M.K., Choo, C.C., Phua, G.Z.M., Teo, D.J.R., Zhu P.C., Choong, C., Wong, M.T.C. and Tan, N.S. (2017) Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression. Sci Rep. 7(1):6303. doi: 10.1038/s41598-017-05869-x.
  8. Baek, J.S., Yeo, E.W., Lee, Y.H., Tan, N.S. and Loo, S.C.J. (2017) Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases. Drug Des Devel Ther. 11:1707-1717.
  9. Tan, Z.W., Teo, Z.Q., Tan-Jujita, C., Choo, C.C., Loo, W.S., Song, Y., Tam, Z.Y., Ng, S.P., Koh, H.Z., Ng, Y.S., Shochat, S.G., Yau, Y.H., Zhu, P.C., Tan, N.S. (2017) ANGPTL4 T266M variant is associated with reduced cancer invasiveness. BBA (Mol. Cell Res.) 1864(10):1525-1536.
  10. Wu, Y.L., Engl, W., Hu, B., Cai, P., Leow, W.R., Tan, N.S., Lim, C.T. and Chen, X. (2017) Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy. ACS Nano. 11(7):6996-7005.
  11. Oteng, A.B., Bhattacharya. A., Brodesser, S., Qi, L., Tan, N.S. and Kersten, S. (2017) Feeding Angptl4-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites. J Lipid Res. 58(6):1100-1113. doi: 10.1194/jlr.M074278.
  12. Lek, S.M., Ku, C.W., Allen, J.C., Malhotra, R., Tan, N.S., Ostbye, T., Tan, T.C. (2017) Validation of serum progesterone <35nmol/L> as a predictor of miscarriage among women with threatened miscarriage. BMC Pregnancy Childbirth. 17(1):78. doi: 10.1186/s12884-017-1261-4.
  13. Phua, T., Sng, M.K., Tan, E.H.P., Chee, D.S.L., Li, Y., Wee, J.W.K., Teo, Z.Q., Chan, J.S.K., Lim, M.M.K., Tan, C.K., Zhu, P.C., Arulampalam, V. and Tan, N.S. (2017) Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin. Sci Rep. 7:44351. doi: 10.1038/srep44351.
  14. Wang, J.K., Luo, B., Guneta, V., Li, L, Foo, S.E.M., Dai, Y., Tan, T.T.Y., Tan, N.S., Choong, C., Wong, M.T.C. (2017) Supercritical carbon dioxide extracted extracellular matrix material from adipose tissue. Mater Sci Eng C. 75:349-358. doi: 10.1016/j.msec.2017.02.002.
  15. Chan, J.S.K., Tan, M.J., Sng, M.K., Teo, Z.Q., Phua, T., Choo, C.C., Li, L., Zhu, P.C. and Tan, N.S. (2017) Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress. Cell Death Dis. 8(1):e2562.
Publications before 2017 can be found in researchgate.
https://www.researchgate.net/profile/Nguan_Soon_Tan