Tan Nguan Soon, Andrew


Selected Publications

  1. Lek, S.M., Ku, C.W., Allen, J.C., Malhotra, R., Tan, N.S., Ostbye, T., Tan, T.C. (2017) Validation of serum progesterone <35nmol/L> as a predictor of miscarriage among women with threatened miscarriage. BMC Pregnancy Childbirth 17(1):78. doi: 10.1186/s12884-017-1261-4.
  2. Phua, T., Sng, M.K., Tan, E.H.P., Chee, D.S.L., Li, Y., Wee, J.W.K., Teo, Z.Q., Chan, J.S.K., Lim, M.M.K., Tan, C.K., Zhu, P.C., Arulampalam, V. and Tan, N.S. (2017) Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin. Sci Rep 7:44351. doi: 10.1038/srep44351.
  3. Wang, J.K., Luo, B., Guneta, V., Li, L, Foo, S.E.M., Dai, Y., Tan, T.T.Y., Tan, N.S., Choong, C., Wong, M.T.C. (2017) Supercritical carbon dioxide extracted extracellular matrix material from adipose tissue.Mater Sci Eng C. vol 75: 349–358 http://dx.doi.org/10.1016/j.msec.2017.02.002
  4. Chan, J.S.K., Tan, M.J., Sng, M.K., Teo, Z.Q., Phua, T., Choo, C.C., Li, L., Zhu, P.C., Tan, N.S. (2017) Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress. Cell Death Dis. 8, e2562; doi:10.1038/cddis.2016.492
  5. Jain, N., Kalailingam, P., Tan, K.W., Tan, H.B., Sng, M.K., Chan, J.S., Tan, N.S., Thanabalu ,T. (2016) Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure. Sci Rep. 6:38109. doi: 10.1038/srep38109.
  6. Goh, Y.Y., Yan, Y.K., Tan, N.S., Goh, S., Li, S., Teoh, Y.C., Lee, P.P.F. (2016) Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex. Sci Rep. 6:36868. doi: 10.1038/srep36868.
  7. Guneta, V., Tan, N.S., Chan, J.S.K., Tanavde, V., Lim, T.C., Wong, T.C.M., Choong, C. (2016). Comparative study of adipose-derived stem cells and bone marrow-derived stem cells in similar microenvironmental conditions. Exp. Cell Res. 348(2):155-164. doi: 10.1016/j.yexcr.2016.09.012
  8. Tan, N.S.*, Vázquez-Carrera, M., Montagner, A., Sng, M.K., Guillou, H., Wahli, W.* (2016), Transcriptional control of health and disease by the nuclear receptor PPARβ/δ.  Prog. Lipid Res. 64:98-122. doi: 10.1016/j.plipres.2016.09.001  *co-corresponding authors
  9. Yang, H., Nguyen, K.T., Leong, D., Tan, N.S., Tay, C.Y. (2016) A soft material approach to induce oxidative stress in mesenchymal stem cells for functional tissue repair. ACS Appl. Mater. Interfaces 8(40):26591-26599.
  10. Ang, Z., Er, J.Z., Tan, N.S., Lu, J., Liou, Y.C., Ding, J.L. (2016) Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Sci Rep. 6:34145. doi: 10.1038/srep34145.
  11. Baek, J.S., Choo, C.C., Qian, C., Tan, N.S., Shen, Z., Loo, S.C. (2016) Multi-Drug-Loaded Microcapsules with Controlled Release for Management of Parkinson's Disease. Small. 12(27):3712-22. doi: 10.1002/smll.201600067.
  12. Hartrianti, P., Nguyen, T.H.L., Johanes, J., Chou, S.M,, Zhu, P., Tan, N.S., Tang, M.B.Y., Ng, K.W. (2016) Fabrication and Characterization of a Novel Crosslinked Human Keratin-Alginate Sponge. J Tissue Eng Regen Med. doi: 10.1002/term.2159
  13. Wang, J.K., Xiong, G.M., Luo, B., Choo, C.C., Yuan, S., Tan, N.S., Choong, C. (2016) Surface modification of PVDF using non-mammalian sources of collagen for enhancement of endothelial cell functionality. J Mater Sci Mater Med. Mar;27(3):45.
  14. Wong, H.K., Lam, I., Wen, F., Chong, S.K.M., Tan, N.S., Chan, J., Pal, M. and Tan, L.P. (2016). Novel method to improve vascularization of tissue engineered constructs with biodegradable fibers. Biofabrication. 8:015004 doi: 10.1088/1758-5090/8/1/015004.
  15. Chun, Y.Y., Wang, J.K., Tan, N.S., Chan, P.P., Tan, T.T., Choong, C. (2016) A Periosteum-Inspired 3D Hydrogel-Bioceramic Composite for Enhanced Bone Regeneration. Macromol Biosci. Feb;16(2):276-87.
  16. Chong Y.K., Sandanaraj, E., L.W.H., Thangaveloo, M., Tan, M.S.Y., Koh, G.R.H., Toh, T.B., Lim, G.G.Y., Holbrook, J.D., Kon, O.L., Nadarajah, M., Ng, I., Ng, W.H., Tan, N.S., Lim, K.L., Tang, C., Ang, B.T. (2015). ST3GAL1-associated transcriptomic program in glioblastoma relates to tumor growth, invasion and prognosis. J. Natl. Cancer Inst.  108(2). pii: djv326.
  17. Chew, R.J., Sepp, K., Li, B.B., Li, Y., Zhu, P.C., Tan, N.S. and Leung P.H. (2015). An Approach to the Efficient Syntheses of Chiral Phosphino-Carboxylic Acid Esters. Adv. Synth. Catal. 357: 3297–3302. doi: 10.1002/adsc.201500638.
  18. Chun, Y.Y., Wang, J.K., Tan, N.S., Chan, P.P., Tan, T.T. and Choong, C. (2015) A Periosteum-Inspired 3D Hydrogel-Bioceramic Composite for Enhanced Bone Regeneration. Macromol Biosci. 2015 Oct 7. doi: 10.1002/mabi.201500258.
  19. Jia, Y.X., Chew, R.J., Li, B.B., Zhu, P.C., Li, Y., Pullarkat, S.A., Tan, N.S. and Leung P.H. (2015). Palladacycle Promoted Base Controlled Regio- and Enantioselective Hydrophosphination of 2-Pyridylacrylate/amide and the Cytotoxicity of their Gold Complexes. Dalton Trans. Oct 28;44(40):17557-64.
  20. Lee, W.L., Guo, W.M., Ho, V.H.B., Saha, A., Chong, H.C., Tan, N.S. Tan, E.Y. and Loo, S.C.J. (2015) Delivery of Doxorubicin and Paclitaxel from Double-Layered Microparticles: The Effects of Layer Thickness and Dual-Drug vs. Single-Drug Loading. Acta Biomaterialia 27:53-65. doi: 10.1016/j.actbio.2015.08.051.
  21. Li, L., Chow, V.T.K. and Tan, N.S. (2015) Targeting Vascular Leakage in Lung Inflammation. Oncotarget. (Aug 14;6(23):19338-9.)
  22. Liu Q, Zhu Y, Yong WK, Sze NS, Tan NS, Ding JL. (2015) Cutting Edge: Synchronization of IRF1, JunB, and C/EBPβ Activities during TLR3-TLR7 Cross-Talk Orchestrates Timely Cytokine Synergy in the Proinflammatory Response. J Immunol. (Aug 1;195(3):801-5. doi: 10.4049/jimmunol.1402358.)
  23. Wang JK, Xiong GM, Zhu M, Özyilmaz B, Castro Neto AH, Tan NS, Choong C. (2015) Polymer-Enriched 3D Graphene Foams for Biomedical Applications. ACS Appl Mater Interfaces. 2;7(15):8275-83.
  24. Li, B.B., Jia, Y.X., Zhu, P.C., Chew, R.J., Li.,Y., Tan, N.S., Leung, P.H. (2015) Highly Selective Anti-Cancer Properties of Ester Functionalized Enantiopure Dinuclear Gold(I)-diphosphine. Eur. J. Med. Chem. Jun 15;98:250-5.
  25. Xiong, G.M., Yuan, S., Wang, J.K., Do, A.T., Tan, N.S., Yeo, K.S. and Choong, C. (2015) Imparting Electroactivity to Polycaprolactone Fibers with Doped Polypyrrole: Modulation of Hemocompatibility and Inflammatory Responses. Acta Biomaterialia. May 14. pii: S1742-7061(15)00220-2.
  26. Tay, C.Y., Wu, Y-L., Cai, P., Tan, N.S., Venkatraman, S., Chen X., and Tan, L.P. (2015) Bio-inspired micropatterned hydrogel to direct and deconstruct hierarchical processing of geometry-force signals by human mesenchymal stem cells during smooth muscle cell differentiation. NPG Asia Materials 7, e199; doi:10.1038/am.2015.66
  27. Ku, C.W., Allen, J.C.Jr, Malhotra, R., Chong, H.C., Tan, N.S., Østbye, T., Lek, S.M., Lie, D. and Tan, T.C. (2015) How can we predict the risk of spontaneous miscarriage among women experiencing threatened miscarriage? Gynecol. Endocrinol. Jun 2:1-5.
  28. Montagner, A., Wahli, W. and Tan, N.S. (2015) Nuclear Receptor Peroxisome Proliferator Activated Receptor (PPAR) β/δ in Skin Wound Healing and Cancer. Eur. J. Dermatol. (in press)

  29. Tan, N.S. and Wahli, W. (2015) Nuclear Hormone Receptors and Epidermal Differentiation in Lipids and Skin Health. Pappas Apostolos (Ed.) Springer Publishing. ISBN: 978-3-319-09942-2. Page 91-108.
  30. Wang, S., Zhenxing, W., Foo, SE., Tan, N.S., Yuan, Y., Lin, W., Zhang, Z., Ng, K.W. (2015) Culturing Fibroblasts in 3D Human Hair Keratin Hydrogels. ACS Appl Mater Interfaces. 11;7(9):5187-98.
  31. Li, L., Chong, H.C., Ng, S.Y., Kwok, K.W., Teo, Z.Q, Tan, E.H.P., Choo, C.C., Seet, J.E., Choi, H.W., Buist, M.L., Chow, V.T.K. and Tan, N.S. (2015) Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia. Cell Reports 10(5):654-663
  32. Luo, B., Yuan, S., Foo, S. E. M., Wong, M. T. C., Lim, T. C., Tan, N. S. and Choong, C. (2015), From Flab to Fab: Transforming Surgical Waste into an Effective Bioactive Coating Material. Adv. Healthcare Mater. Mar 11;4(4):613-20
  33. Wang, X.L., Sng, M.K., Foo, S., Chong, H.C., Lee, W.L., Tang, M.B.Y., Ng, K.W., Luo, B., Choong, C., Wong, M.T.C., Tong, B.M.K., Chiba, S., Loo, S.C.J., Zhu, P.C. and Tan, N.S. (2015) Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment. J. Control. Release 197: 138-147