Tan Nguan Soon, Andrew


Selected Publications


  • Chen, H., Lui, Y.S., Tan, Z.W., Lee, J.Y.H., Tan, N.S. and Tan, L.P. (2019).  Migration and Phenotype Control of Human Dermal Fibroblasts by Electrospun Fibrous Substrates. Adv Healthcare Mater. (in press)
  • Liao, Z., Chua, D. and Tan, N.S. (2019) Reactive oxygen species: a volatile driver of field cancerization and metastasis. Mol. Cancer (in press)
  • Cheng, H.S., Lee, J.X.T., Wahli, W. and Tan, N.S. (2019) Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment. Mol. Cancer (in press)
  • Oh HYP, Ellero-Simatos S, Manickam R, Tan NS, Guillou H, Wahli W. (2019). Depletion of Gram-Positive Bacteria Impacts Hepatic Biological Functions During the Light Phase. Int J Mol Sci. 14;20(4). pii: E812. doi: 10.3390/ijms20040812


  • Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W. (2018) Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Oncogene. Dec 5. doi: 10.1038/s41388-018-0592-6.
  • Cao H, Lee MKH, Yang H, Sze SK, Tan NS, Tay CY. (2018) Mechanoregulation of cancer-associated fibroblasts phenotype in 3D interpenetrating hydrogel networks. Langmuir Nov 27. doi: 10.1021/acs.langmuir.8b02649.
  • Lim, M.M.K., Wee, J.W.K.,Soong, J.C., Chua, D., Tan, W.R., Lizwan, M., Li, Y., Teo, Z., Goh, W.W.B., Zhu, P.C. and Tan, N.S. (2018) Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs. Mol. Cancer Oct 20;17(1):152. doi: 10.1186/s12943-018-0904-z
  • Ku, C.Y., Allen Jr, J.C., Lek, S.M., Chia, M.L., Tan, N.S. and Tan T.C. (2018). Serum progesterone distribution in normal pregnancies compared to pregnancies complicated by threatened miscarriage from 5 to 13 weeks gestation: a prospective cohort study. BMC Pregnancy and Childbirth. 18(1):360. doi: 10.1186/s12884-018-2002-z.
  • Lim, H.Y., Lim S.Y., Tan, C.K., Thiam, C.H., Goh, C.C., Carbajo, D., Chew, S.H.S., See, P., Chakarov, S., Wang, X.N., Lim, L.H., Johnson, L.A., Lum, J., Fong, C.Y., Bongso, A., Biswas, A., Goh, C., Evrard, M., Yeo, K.P., Basu, R., Wang, J.K., Tan, Y., Jain, R., Tikoo, S., Choong, C., Weninger, W., Poidinger, M., Stanley, R.E., Collin, M., Tan, N.S., Ng, L.G., Jackson, D.G., Ginhoux, F. and Angeli, V. (2018). Hyaluronan receptor LYVE-1 expressing macrophages maintain arterial tone through hyaluronan-mediated regulation of smooth muscle cell collagen. Immunity. pii: S1074-7613(18)30290-5. doi: 10.1016/j.immuni.2018.06.008.
  • Chen, J.P., Montagner, A., Tan, N.S. and Wahli, W. (2018) Insights into the role of PPARb/δ in NAFLD. Intl. J. Mol. Sci. 19(7). pii: E1893. doi: 10.3390/ijms19071893. (review)
  • Yeo, C.K., Vikhe, Y.S., Li, P., Guo, Z., Greenberg, P., Duan, H., Tan, N.S. and Chan-Park, M. (2018). Hydrogel effects rapid biofilm debridement with ex-situ contact-kill to eliminate multi-drug resistant bacteria in vivo. ACS Appl Mater Interfaces. doi: 10.1021/acsami.8b06262
  • Phua, W.W.T., Wong, M.X.Y., Liao, Z and Tan, N.S. (2018) An aPPARent functional consequence in skeletal muscle physiology via peroxisome proliferator activated receptors. Intl. J. Mol. Sci. 19(5). pii: E1425. doi: 10.3390/ijms19051425. (review)
  • Sng, M.K., Chan, J.S.K., Teo, Z.Q., Phua, T., Tan, E.H.P., Wee, J.W.W., Koh, N.J.N., Tan, C.K., Chen, J., Pal, M., Tong, B.M.K., Tnay, Y.L., Ng, X.R., Zhu, P.C., Chiba, S., Wang, X., Wahli, W. and Tan, N.S. (2018) Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. Cell Discov. 4:15. doi: 10.1038/s41421-018-0014-5.
  • Tan, E.H.P., Sng, M.K., How, I.S.B., Chan, J.S.K., Chen, J., Tan, C.K., Wahli, W. and Tan, N.S. (2018) ROS release by PPARb/δ-null fibroblasts reduces tumor load through epithelial antioxidant response. Oncogene doi:10.1038/s41388-017-0109-8
  • Liao, Z., Tan, Z.W., Zhu, P.C., and Tan, N.S. (2018) Cancer-associated fibroblasts in tumor microenvironment–accomplices in tumor malignancy. Cell Immunol. pii: S0008-8749(17)30222-8. doi 10.1016/j.cellimm.2017.12.003(review)
  • Chan, J.S.K., Sng, M.K., Teo, Z.Q., Chong, H.C., Twang, J.S. and Tan, N.S. (2018) Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors. Oncogene 37(2):160-173. doi: 10.1038/onc.2017.319

Publications (with full-text) and Current Research Projects can be found in ResearchGate.