Lescar, Julien


Selected Publications

  1. Fan H, Ooi A, Tan YW, Wang S, Fang S, Liu DX & Lescar J (2005) Crystal Structure of the N-terminal Domain from the Nucleocapsid Protein of Coronavirus Infectious Bronchitis Virus and multimerization properties. Structure 13, 1859-1868
  2. Ting X, Ooi A, Lee HC, Wilmouth R, Liu D.X, Lescar J. (2005) Structure of the SARS coronavirus Main proteinase as an active C2 crystallographic dimer. Acta Cryst F61, 964-966
  3. Shi M, Sundramurthy K, Liu B, Tan SM, Law A & Lescar J (2005) The crystal structure of the PSI/Hybrid domain/I-EGF1 segment from the Human Integrin β2 subunit at 1.8 Å resolution. > J. Biol. Chem. 280, 30586-30593
  4. Xu T., Sampath A, Chao A, Wen D, Nanao M, Chene P, Vasudevan S G & Lescar J (2005) Structure of the dengue virus helicase/NTPase catalytic domain at 2.4 Å resolution. J. Virol. 79, 10278-10288
  5. Chu J., Rajamanonmani R., Li J, Bhuvanakantham R., Lescar J, Ng M-L (2005) Inhibition of West Nile virus entry by using a recombinant Domain III from the envelope glycoprotein. J. Gen. Virol. 86, 405-412
  6. Bressanelli S, Stiasny K., Allison S., Stura E.A., Duquerroy S., Lescar J., Heinz F.X., Rey F.A. (2004) Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation. EMBO J.23, 728-738
  7. Lescar J ., Loris R., Mitchell E., Gautier C., Chazalet V., Cox V., Wyns L., Pérez S., Breton C., Imberty A. (2002) Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia: crystal structure of metal-free GSI-B4 and molecular basis for metal binding and monosaccharide specificity J. Biol. Chem.277, 6608-6614
  8. Delarue M., Boulé J-B, Lescar J., Expert-Bezançon N., Jourdan N., Sukumar N., Rougeon F., Papanicolaou C. (2002) Crystal structure of a template independent DNA polymerase: murine Terminal deoxynucleotidyl Transferase EMBO J.21, 427-439
  9. Rezacova P., Lescar J., Brynda J., Fabry M., Horejsi M., Sedlacek J., Bentley G.A. (2001) Structural basis of HIV-1 and HIV-2 Protease Inhibition by a monoclonal antibody Structure9, 887-895
  10. Lescar J ., Roussel A., Wien M.W., Navaza J., Fuller S.D., Wengler G., Wengler G., Rey F.A. (2001) The fusion glycoprotein shell of Semliki Forest Virus: an icosahedral assembly primed for fusogenic activation at endosomal pH. Cell 105, 137-148