Lin Chun Ling, Valerie

Share     

Selected Publications

  1. ZeYi Zheng and Valerie CL. Lin (2008) Anti-estrogenic Effect of Unliganded Progesterone Receptor is Estrogen-Selective in Breast Cancer Cells MCF-7. Cancer letters May 12. [Epub ahead of print]
  2. Joyce CL Leo and Valerie CL Lin (2008) The activity of progesterone receptor isoform A and B are differentially modulated by their ligands in a gene-selective manner. International Journal of Cancer 122(1):230-43.
  3. ZeYi Zheng, Si-Min Zheng, Boon Huat Bay, Swee Eng Aw, Valerie CL. Lin (2007) Anti-Estrogenic Mechanism of Unliganded Progesterone Receptor Isoform B in Breast Cancer Cells. Breast Cancer Research and Treatment, 110(1):111-25.
  4. Maria Stepanova, Feng Lin and Valerie CL Lin(2006) Establishing a statistic model for recognition of steroid hormone response elements. Computational Biology and Chemistry 30: 339-47
  5. Shenglan Cao, J. K. Iyer, and Valerie CL. Lin (2006) Identification of tetratricopeptide repeat domain 9, a hormonally regulated protein. Biochemical and Biophysical Research Communications. 345: 310 – 317.
  6. Zeyi Zheng, Boon Huat Bay, Swee Eng Aw, and Valerie CL Lin (2005) A novel anti-estrogenic mechanism in progesterone receptor-transfected breast cancer cells. Journal of Biological Chemistry. 280: 17480 – 17487.
  7. Joyce CL Leo, Suk Mei Wang, Chun Hua Guo, Swee Eng Aw, Yi Zhao, Jin Ming Li, Kam M. Hui and Valerie CL Lin (2005) Gene regulation profile reveals consistent anti-cancer properties of progesterone in hormone-independent breast cancer cells transfected with progesterone receptor. International Journal of Cancer, 117, 561 – 568.
  8. Joyce CL Leo, Chunhua Guo, Chow Thai Woon, Swee Eng Aw and Valerie CL Lin (2004) Glucocorticoid and mineralocorticoid cross-talk with progesterone receptor to induce focal adhesion and growth inhibition in breast cancer cells. Endocrinology 145: 1314 – 1321.
  9. Valerie CL Lin, Chow-Thai Woon, Swee Eng Aw and Chunhua Guo (2003) Distinct molecular pathways mediate progesterone-induced growth inhibition and focal adhesion. Endocrinology 144: 5650-5657.
  10. Valerie CL Lin, Rongxian Jin, Puay-Hoon Tan, Swee Eng Aw, Chow-Thai Woon, and Boon Huat Bay (2003) Progesterone induces cellular differentiation in MDA-MB 231 breast cancer cells transfected with progesterone receptor complementary DNA. American Journal of Pathology 162: 1781 – 1787.
  11. Valerie CL. Lin, Swee Eng Aw, Eng Hen Ng, Esther H-L Ng and Sanaul H Chowdhury (2001) Effect of progesterone on the invasive properties and tumor growth of progesterone receptor (PR)-transfected breast cancer cells MDA-MB-231. Clinical Cancer Research 7: 2880-2886.
  12. Valerie CL. Lin, Swee Eng Aw, Eng Hen Ng, Esther H-L Ng and Michelle G-K. Tan (2001) RU486 inhibits cell growth via mechanisms distinct from that of progesterone in breast cancer cells transfected with progesterone receptor cDNA. British Journal of Cancer 85: 1978 - 1986.
  13. Valerie CL. Lin, Eng Hen Ng, Swee Eng Aw, Michelle G-K. Tan, Esther H-L. Ng, Boon Huat Bay (2000) Progesterone induces cell spreading and focal adhesion in breast cancer cells MDA-MB-231 transfected with progesterone receptor cDNA. Molecular Endocrinology 14(3): 348-58.
  14. Rongxian Jin, Boon Huat Bay, VTK Chow, Puay-Hoon Tan and Valerie CL Lin (2000) Metallothionein 1E mRNA is highly expressed in estrogen receptor negative human invasive ductal breast cancer. British Journal of Cancer 83(3): 319-23.
  15. Valerie CL. Lin, Eng Hen Ng, Swee Eng Aw, Michelle G-K. Tan, Esther H-L. Ng, Vivian S-W Chan and Gay Hui Ho (1999) Progestins inhibit the growth of MDA-MB-231 cells transfected with progesterone receptor cDNA. Clinical Cancer Research 5: 395-404.
  16. Eng-Hen Ng, Chen Yang Ji, Puay-Hoon Tan, Valerie CL Lin, Khee-Chee Soo and Kok-Onn Lee (1998) Altered serum levels of insulin-like growth factor binding protein in breast cancer patients. Annals of Surgical Oncology, 5(2):194-201.