Koh Cheng Gee

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Selected Publications

  1. Bernitt E, Koh CG, Gov N and Dobereiner HG. 2015. Dynamics of actin waves on patterned substrates: a quantitative analysis of circular dorsal ruffles. PLoS One 10: e0115857.
  2. Hoon JL, Li HY and Koh CG*. 2014. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle, 13: 2459-2468.
  3. Phang HQ, Hoon JL, Lai SK, Zeng Y, Chiam KH, Li HY and Koh CG*. 2014. POPX2 phosphatase regulates the KIF3 kinesin motor complex. Journal of Cell Science, 127:727-739.
  4. Zhang S, Guo T, Chan H, Sze SK, and Koh CG*. 2013. An integrative transcriptome and proteome study to identify the signaling network regulated by POPX2 phosphatase. Journal of Proteome Research, 12: 2525-2536.
  5. Tay CY, Koh CG, Tan NS, Leong DT, and Tan LP. 2013 Mechano-regulation of stem cell fate via micro-nanoscale manipulation for regenerative medicine. Nanomedicine, 8:623-638.
  6. Chan KS, Koh CG* and Li HY*. 2012. Mitosis targeted anti-cancer therapies: where they stand. Cell Death and Disease. 3: e411. *corresponding authors.
  7. Hoon JL, Wong WK, and Koh CG*. 2012. Functions and regulation of circular dorsal ruffles. Molecular and Cellular Biology. 32: 4246-4257.
  8. Lee YP, Wong CH, Chan KS, Lai SK, Koh CG* and Li HY*.  2012. In vivo FRET revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase. PLoS One, 7: e45836. *corresponding authors.
  9. Dutta B, Adav SS, Koh CG, Lim SK, Meshorer E, Sze SK. 2012. Elucidating the temporal dynamics of chromatin associated protein release upon DNA digestion by quantitative proteomic approach. Journal of Proteomics, 75: 5493-5506.
  10. Heng YW, Lim HH, Mina T, Utomo P, Zhong S, Lim CT and Koh CG*. 2012. TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation. Journal of Cell Science, 125: 1579-1590.
  11. Zeng Y, Lai T, Koh CG, LeDuc PR, and Chiam KH. 2011. Investigating circular dorsal ruffles through varying substrate stiff ness and mathematical modeling. Biophysical Journal, 101: 2121-2130.
  12. Singh P, Gan CS, Guo T, Phang HQ, Sze SK and Koh CG*. 2011. Investigation of POPX2 phosphatase functions by comparative phosphoproteomic analysis. Proteomics, 11: 2891-2900.
  13. Heng YW and Koh CG*. 2010. Actin cytoskeleton dynamics and the cell division cycle. International Journal of Biochemistry and Cell Biology, 42: 1622-1633.
  14. Susila, A, Chan H, Loh AXW, Phang HQ, Wong ET, Tergaonkar V and Koh CG*. 2010. POPX2, the negative regulator of the kinase PAK, regulates cancer cell motility and invasiveness. Cell Cycle, 9: 179-187.
  15. Wong CH, Chan H, Ho CY, Lai SK, Chan KS, Koh CG* and Li HY*. 2009. Apoptotic histone modification inhibits nuclear transport by regulating RCC1. Nature Cell Biology, 11: 36-45. *corresponding authors.
  16. Tan TL, Fang N, Neo TL, Singh P, Zhang J, Zhou R, Koh CG, Chan V, Lim SG, and Chen WN. 2008. Rac1 GTPase is activated by hepatitis B virus replication-involvement of HBX. Biochemica et Biophysica Acta (BBA)-Molecular Cell Research, 1783: 360-74.
  17. Xie Y, Tan EJ, Wee S, Manser E, Lim L and Koh CG*. 2008. Functional Interactions between POPX2 phosphatase and mDia modulate RhoA pathways. Journal of Cell Science, 121: 514-521.
  18. Koh CG*. 2007. Rho GTPases and their regulators in neuronal functions and development. NeuroSignals, 15: 228-237.
  19. Koh CG*, Tan EJ, Manser E, and Lim L. 2002. The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. Current Biology, 12: 317-321.
  20. Koh CG*, Manser E, Zhao ZS, Ng CP and Lim L. 2001. β1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles. Journal of Cell Science, 114: 4239-4251.
  21. Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T and Lim L. 1998. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Molecular Cell, 1: 183-192.
  22. Koh CG*, Oon SH and Brenner S. 1997. Serine/threonine phosphatases of the pufferfish, Fugu rubripes. Gene, 198: 223-228.
  23. Koh CG*, Barnett L and Brenner S. 1993. Vectorsλ200g and λ200c: two useful derivatives of λl2001.  Gene, 130: 117-119.